Dr. Aimie Apigian: The Biology of Trauma, Nervous System Safety and Somatic Healing

Longevity isn’t just workouts, supplements, and recovery tools, it starts with nervous system health. 

In this episode, Dr. Aimie Apigian explains what trauma actually is (not a label, but a measurable physiological response), how the body shifts from stress into overwhelm, and why “pushing through” often turns into years of avoidance, numbing, and hidden internal strain.

She breaks down the biology behind the trauma response, including the role of adrenaline, cortisol timing, and how mitochondrial capacity influences resilience. You’ll also learn her practical, body-based approach to creating “safe enough” in real time, plus the three phases of healing: safety, support, and expansion, so you don’t stay stuck avoiding triggers forever.

In this conversation:

  • Stress vs trauma response (and what changes physiologically)

  • Why adrenaline drives the response and cortisol arrives later

  • How the body stores trauma as patterns, not just memories

  • The 3 nervous system states and the thoughts they generate

  • A simple somatic exercise to build safety in the body

  • Why devices/meds can be bridges, not the destination

  • Using biomarkers + wearables without fooling yourself

  • Why modern media can create vicarious trauma

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CHAPTERS

00:00:00 Trailer / Cold Open Highlights

00:01:31 Trauma, Stress, and Why Longevity Starts With the Nervous System

00:05:33 Why “Pushing Through” Stops Working And How Stress Becomes Biology

00:14:54 ACE Score and Autoimmunity: The Long Shadow of Childhood Stress

00:18:33 Why the Body Holds Trauma and How It Releases

00:21:19 Stress Patterns You Can See in Biomarkers

00:33:53 Somatic Work: Creating Safety in the Body

00:38:11 “Familiar Is Safe”: Why Change Can Feel Threatening

00:41:42 Biohacks as Bridges: Vagus Nerve Stimulation, Homeostasis, Capacity

00:47:22 Window of Tolerance: Why Healing Must Happen in Phases

00:52:57 Building Capacity Safely (Why More Isn’t Better)

01:00:12 Stress vs Overwhelm: When the Nervous System Tips Into Shutdown

01:02:17 The 3 Survival Mechanisms: Dissociation, Freeze, Energy Conservation

01:05:20 Implicit Memories: Why You Don’t Remember Your Childhood

01:11:30 Relationship Safety: Why You Can’t Outsource “Feeling Safe”

01:17:04 The Three Nervous System States and How Thoughts Change With State

01:33:48 Why Women Report Higher Stress Than Men

01:36:57 What Partners Often Misread About Healing and Safety

01:44:49 Wearables, HRV, and Knowing Your Real Capacity

01:54:32 Closing and Where to Find Dr. Aimie

Connect with Kayla:


Instagram: https://www.instagram.com/kaylabarnes/

TikTok: https://www.tiktok.com/@femalelongevity

Twitter:https://x.com/femalelongevity

Website:https://www.kaylabarnes.com/

Spotify:https://open.spotify.com/show/4OLWWn22...

Apple: https://podcasts.apple.com/us/podcast...

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com


Learn more about Dr. Aimie Apigian, MD:

Instagram: https://www.instagram.com/draimie/
YouTube: https://www.youtube.com/c/DrAimieApigian
Website: https://www.biologyoftrauma.com/
Order her Book “The Biology of Trauma”:https://www.biologyoftrauma.com/book

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Cynthia Thurlow, NP: Perimenopause, Insulin Resistance and Midlife Metabolism